Dose dependent effect of silver nitrate on enhanced production of gymnemic acid in cell suspension cultures of Gymnemasylvestre R. Br

نویسندگان

چکیده


 Introduction and Aim: Gymnemasylvestre is rich source of triterpenoid saponins popularly known for its anti-diabetic potential. Gymnemic acid chiefly responsible therapeutic In fact, gymnemic a group compounds as gymnemagenin (oleanane group) other related are gymnemasides (dammaranes). Despite immense medicinal importance, very few studies were conducted enhanced production. The present study undertaken the production using silver nitrate (AgNO3) effective elicitor influence on culture parameters. Materials Methods:Callus was initiated cell suspension establishment used to effect. Different doses AgNO3 at varied periods mediated effect growth index, pH, EC MDA content conducted. estimated by HPLC.
 Results:Cell positively influenced with concomitant change in pH medium. Apparent rise response increased dosage observed correlated Dose dependent different under study. Conclusion: Substantial improvements produced 100µM can be industrial scale. It also offers opportunities studying parameters

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ژورنال

عنوان ژورنال: Biomedicine

سال: 2021

ISSN: ['2211-8020', '2211-8039']

DOI: https://doi.org/10.51248/.v41i1.527